Distribution of Antibodies in the Serum and Organs of Rabbits

[摘要] In a previous study of the distribution of agglutinins in the serum and organs of rabbits (1), it has been shown that the liver, spleen, kidney, lung, uterus and skin of actively or passively immunized rabbits accumulate approximately the same amount of antibodies per gram of organ. A decided difference was observed, however, in the rate of accumulation in these organs. In passively immunized animals the accumulation of agglutinins is rapid in the liver, spleen, kidney and lung. In these organs the accumulation was completed within from ten to fifteen minutes after the immune serum had been injected into the ear vein. On the other hand, in the uterus and particularly in the skin, the accumulation of antibodies continued for several hours.In the first paper of this series it was suggested that the relatively early appearance of antibodies in the liver, spleen, kidney and lung may be connected with the relatively greater rate of lymph flow from these organs.

[学科分类] 生物科学（综合）