Studies of a Complement-Fixing Antigen from Group A Streptococcal l Forms

[摘要] Extracts of L forms of a type 19 strain of group A streptococcus were found to react against certain animal and human sera in the Kolmer complement-fixation test. Sera from human subjects with presumably recent streptococcal experience were more often reactive than that from control groups. Antisera from rabbits immunized with group A and group C streptococci and with homologous group A L forms uniformly exhibited significant reactivity, whereas control rabbits and those immunized with other species and genera of Gram-positive cocci did not. Complement-fixing antigen was not extractable from the whole streptococcal cell by the same procedures, nor could the anti-L titer be reduced or removed from a human serum by adsorption with streptococci or cell wall preparations.

[学科分类] 生物科学（综合）