Studies of Aggregated γ-Globulin

[摘要] Injection of aggregated human γ-globulin into the skin of guinea pig, rat and man produced inflammatory changes. Histologically, the injection sites of guinea pigs and rats demonstrated marked polymorphonuclear and mononuclear infiltrations that were maximal at about 24 hr.Intravenous administration of aggregated human γ-globulin, which is strikingly anticomplementary in vitro , rendered the sera of recipient animals deficient in hemolytically active C′ for several hours.

[学科分类] 生物科学（综合）