Studies on the Antigens of Pasteurella Pestis and Pasteurella Pseudotuberculosis

[摘要] Using a gel diffusion technique with absorbed antisera, 18 different antigens of Pasteurella pestis and Pasteurella pseudotuberculosis have been observed. Five of these were specific for P. pestis , two were specific for P. pseudotuberculosis and the remainder were produced by both organisms. When sera obtained from guinea pigs immunized with four different vaccines were analyzed a promising correlation was observed between the presence of a specific circulating antibody, anti-L, and immunity to pneumonic plague. However, purification of L antigen and subsequent injection of the purified material into guinea pigs induced the formation of L antibodies but did not protect the animals against pneumonic plague.

[学科分类] 生物科学（综合）