Investigation of the Cataphoresis of Toxin and Antitoxin in the “Field and Teague” and in Other Apparatus

[摘要] Numerous investigations of the nature of toxin and antitoxin have supported the view that they are amphoteric colloids, and either are proteins, or are closely adherent to proteins (1). Field and Teague (2) in 1907, however, published, the results of an experiment which indicated that both toxin and antitoxin were positive colloids which migrated to the cathode whether the solution containing them was acid or alkaline. This work, if confirmed, would afford a means for the separation of toxin and antitoxin from protein, since protein in alkaline solution is known to migrate to the anode. Because the exact hydrogen ion concentrations of the solutions used were not determined by these authors, we decided to electrolyze toxin and antitoxin solutions at a series of definite hydrogen ion concentrations, using the apparatus which they described.

[学科分类] 生物科学（综合）