Studies on the “Toxins” of Hemolytic Streptococci

[摘要] We have prepared three sorts of polyvalent toxins, scarlatinal, erysipelas and suppurative, by mixing several toxic preparations selected through skin reactions on human subjects and three sorts of antitoxin by immunization with these toxins. From the neutralization tests of polyvalent and monovalent toxins by these antitoxins on white pigs the following conclusions may be drawn: 1. 1. Scarlatinal, erysipelas and suppurative antitoxic sera equally neutralize scarlatinal, erysipelas and suppurative toxins.2. 2. The neutralizing action of these sera is most marked in the case of homologous toxin.3. 3. Scarlatinal antitoxic serum prepared by us is more comprehensive in its neutralizing action than the erysipelas serum.4. 4. The results of the neutralization tests with antiscarlatinal serum of monovalent toxins of various strains have shown that the majority of toxic preparations (32 out of 34 strains), regardless of their sources, were neutralized with the exception of that produced by one erysipelas and one scarlatinal strain.A part of the expenses of this investigation was defrayed by a grant from the Antiscarlatinal Committee of the Kwantung Government.

[学科分类] 生物科学（综合）