A Specific Precipitation Test for the Standardization of Type I Antipneumococcus Serum

[摘要] Forty-six type I antipneumococcus sera were tested for precipitative activity with a solution of the type I cellular carbohydrate. The results obtained agreed in 91.3 per cent of the cases with the results obtained by mouse protection tests. Eight concentrated antipneumococcus sera were similarly tested and found to agree in seven instances. The results indicate that the precipitation test described provides a titration which appears to be a reliable index of the development of the protective activity in the course of immunization; in the preliminary evaluation of the serum it can thus replace the more complicated protection test which, at present, however, should still be used in the final standardization.

[学科分类] 生物科学（综合）