Demonstration of Molecular Individuality of HL-A Antigens

[摘要] Partially purified HL-A antigens, isolated by papain digestion from membranes of cultured lymphocytes, were subjected to a combination of immunoabsorbance and polyacrylamide gel electrophoresis. With four alloantisera, specific for the HL-A antigens characteristic of the cell line, each antigen could be completely separated from the other three. The results prove that the four HL-A antigens determined by a single genotype are present on four distinct molecular species.

[学科分类] 生物科学（综合）