On the Spontaneous Immunization of Rabbits to Vaccine Virus

[摘要] It has been shown in previous publications (1, 2) that in the testicle, especially, and also to some degree in certain other organs, there exists a factor which is capable of greatly augmenting the lesions produced by viruses and bacteria. In the course of experiments designed to test the possibility of neutralizing this factor by an antitesticular serum, a number of rabbits were given repeated injections of testicle extract subcutaneously, intravenously and intraperitoneally. As a control, others were similarly injected with spleen extract. In the course of testing the effects of the resultant sera on the factor of testicle extract, it was observed that in certain instances not only was the enhancing power of testicle extract neutralized, but the vaccine virus used in the test was inactivated. An examination was made into this unexpected result.

[学科分类] 生物科学（综合）