Advantages and Disadvantages of the Buffered Diluent for Diphtheria Toxin

[摘要] Previous work by Bunney and White (1) on the buffered diluent described by Glenny, Pope and Waddington (2) substantiated their description of its properties to a degree encouraging further study. Diphtheria toxin diluted in this borax-boric acid solution[1][1] did not lose toxicity in ten weeks at room temperature. Inasmuch as such a diluent might be valuable to the research scientist interested in diphtheria toxin, as well as to those concerned with either the preparation or the use of diphtheria toxin in the Schick test the subject was investigated further. The additional data gained in this study are presented in the present paper.I. Use of the Glenny Diluent in the Study of Diphtheria ToxinThere is need for a suitable diluent for use in studying the chemistry of diphtheria toxin, in which purified toxin could be dissolved in high or low concentrations with equal confidence, with little fear of deterioration under convenient precautions. [1]: #fn-1

[学科分类] 生物科学（综合）