Quantitative Studies in Anaphylaxis

[摘要] Alum-precipitated ovalbumin had a sensitizing capacity in guinea-pigs of from 4 to nearly 400 times greater than that of ovalbumin in saline solution, depending upon the route of administration of the sensitizing dose.For ovalbumin in saline solution the sensitizing capacity of the antigen by intraäbdominal administration was about 1½ times greater than by intravenous injection and nearly 2½ times greater that by subcutaneous administration. Only the latter difference was statistically significant.For alum-precipitated ovalbumin the sensitizing capacity by subcutaneous administration was 2½ times greater than by intraäbdominal administration and 60 times greater than by intravenous injection. Both of these differences were statistically significant.

[学科分类] 生物科学（综合）