ON THE PRESENCE OF POLIOMYELITIS VIRUS IN REGIONAL LYMPH NODES

[摘要] Fifteen fatal human illnesses caused by poliomyelitis viruses were studied in an effort to evaluate the position of lymphatic tissue in the pathogenesis of poliomyelitis. Poliomyelitis virus was detected in various regional lymph nodes obtained from 12 of 15 fatal cases.Evidence that poliomyelitis virus multiplied in lymphatic tissue was not obtained. The findings indicated that the quantity of available virus was significantly less in lymph nodes than in CNS tissues or in the contents of the gastrointestinal tract. The data obtained in 5 patients indicated that substantial amounts of virus were not bound in situ by homotypic antibody.

[学科分类] 儿科学