MONGOLISM (MONGOLOID DEFICIENCY) DURING EARLY INFANCY—SOME NEWLY RECOGNIZED DIAGNOSTIC CHANGES IN THE PELVIC BONES

[摘要] IN MONGOLOID defectives, stigmas in the skeleton have been reported at several sites: hypoplasia of the base of the skull; hypoplasia of the nasal and other facial bones, and dysplasia and hypoplasia of metacarpals and phalanges. Undergrowth of the vertebral bodies and the tubular bones in the extremities is responsible for the dwarfism which is one of the most consistent components of this syndrome. Maturation of the skeleton varies greatly in different mongoloid infants; it may be advancecd, normal, or retarded. At birth practically all infants with mongolism show normal or advanced maturation, in our experience.Spitzer and Robinson found the frontal sinuses to be absent in 26 out of 28 individuals with mongolism in contrast to an absence in 4 to 5 per 100 of the remainder of the general population. Only 2 of the 28 individuals with mongolism showed no dental aplasia. The erupted teeth were commonly stunted, eruption of the permanent teeth was often delayed, and there was a higher incidence of the dental anomalies found than in the general population. No pathognomonic lesions in the teeth were found. The partial anodontia, deformed teeth and delayed eruption resemble the changes found in ectodermal dysplasia and in cleidocranial dysostosis.Smith and McKeown found the mean weights of newly born infants with mongolism to be 2860 gm. in contrast to 3220 gm. for normal newborns. the mean duration of gestation to he shorter for infants with mongolism than for normal newborns, 269 days and 278 days respectively.So far as we have been able to ascertain, stigmas in the pelvic bones of infants with mongolism have not been reported in either anatomical or roentgenographic studies.

[学科分类] 儿科学