ADRENOCORTICOTROPIC HORMONE IN THE THERAPY OF RETROLENTAL FIBROPLASIA

[摘要] Five premature infants thought to be developing retrolental fibroplasia were treated early, vigorously and persistently with ACTH from a single Armour lot. Activity of the ACTH employed was evidenced in each case by physiologic changes in the recipient.One of the five treated patients died during therapy. The mode of death and possible relationship to ACTH administration are discussed.Retrolental fibroplasia progressed in the four remaining treated cases to cicatrix formation behind the lens.ACTH as employed in this study was an ineffective therapeutic agent in retrolental fibroplasia.

[学科分类] 儿科学