DETERMINATION OF SOME STREPTOCOCCAL ANTIBODY TITERS AND ACUTE PHASE REACTANTS IN PATIENTS WITH CHOREA

[摘要] Forty-three patients with chorea were examined by a number of laboratory tests: These consisted of two streptococcal serologic titrations, antistreptolysin-O and antihyaluronidase, and three acute phase tests, the erythrocyte sedimentation rate, and the concentrations of C-reactive protein and mucoproteins in the serum. The patients were divided into two groups, those with apparently "pure" chorea, who did not show any other clinical evidence of rheumatic fever in conjunction with an episode of chorea, or at any other time to our knowledge, and those with some other evidence of rheumatic fever. In the case of each of these tests the frequency distribution of values found in the rheumatic chorea group was different from that of the "pure" chorea group, the former having a higher center and range of distribution. Also, the results of both the acute phase tests and the streptococcal serologic tests gave evidence of contamination of the "pure" chorea group with rheumatic subjects.The data suggest that there are, in fact, two such clinical groups of patients with chorea, and that laboratory aid toward the differential diagnosis between them would be applied in the same way as in other differential diagnoses involving rheumatic fever.

[学科分类] 儿科学