MECHANISM OF CARDIOTOXIC ACTIONS OF TERFENADINE

[摘要] The duration of the QT interval is primarily controlled by the delayed rectifier potassium current. Episodes of torsades de pointes are most likely the result of a quinidine-like effect of the parent drug. A predisposing cause of an elevated serum level of the parent compound could be found in the majority of cases.

[学科分类] 儿科学