SPHEROCYTOSIS AND INCREASED FRAGILITY OCCURRING IN ERYTHROBLASTOSIS FETALIS ASSOCIATED WITH ABO INCOMPATIBILITY

[摘要] Four cases of hemolytic disease of the newborn infant are reported. There was ABO incompatibility and high maternal immune antibody titre after delivery. Immune antibody was demonstrated in the sera of 3 of the 4 infants.The difficulties in making an unequivocal diagnosis are discussed and the diagnostic value of immune antibody in the infant's serum is emphasized.The presence of spherocytosis and altered erythrocyte hypotonic fragility during the hemolytic phase is noted. These findings are similar to cases of acute hemolytic anemia in adults previously reported.

[学科分类] 儿科学