ELECTROENCEPHALOGRAPHIC FINDINGS IN SICKLE CELL ANEMIA

[摘要] Electroencephalographic findings in 38 cases of sickle cell anemia are presented, of which 35 patients were children under 14 years of age.The EEGs were considered to be abnormal in 26 patients. Of special interest was the fact that all children under 6 years of age had abnormal EEGs.In the group as a whole, there were nine patients with a past history or the presence of nervous system symptoms who had normal EEGs, and three in this group whose tracings were thought to be borderline.A brief review of the principal pathologic changes in the brain in sickle cell anemia is presented, and a discussion is given of the way in which these changes might influence brain potentials.Abnormal brain potentials in patients with sickle cell anemia are considered to be due primarily to cerebral anoxia, and secondarily to degenerative processes in nerve cells.Electroencephalography offers a new approach to the determination of the incidence and character of cerebral dysfunction in sickle cell disease.

[学科分类] 儿科学