INVESTIGATION OF AN INFANT BORN OF A MOTHER SUFFERING FROM CIRRHOSIS OF THE LIVER

[摘要] The successful pregnancy and uncomplicated ated delivery of a healthy infant by a young woman suffering from severe cirrhosis of the liver is described.Serial liver function studies in the infant during the neonatal period suggested a degree of hepatic immaturity not dissimilar from that observed in normal newborn infants.Maternal serum alterations are compared with fetal and neonatal findings. Electrophoretic analysis revealed that the fetus had a normal albumin concentration despite a low level in the mother. The serum γ-globulin was elevated in the fetus just as it was in the mother. Serum bilirubin was present in only ½ the concentration in the fetus as in the mother. Differences in lipoproteins and other high molecular weight components were found. The role of placental permeability in relation to these variations is discussed.Serial electrophoretic analyses during the neonatal period indicated a normal catabolic rate for the unusually elevated γ-globulin component in the infant [t½=20 days].

[学科分类] 儿科学