HEREDITARY NONSPHEROCYTIC HEMOLYTIC ANEMIA PRESENTING AS HEMOLYTIC DISEASE OF THE NEWBORN INFANT

[摘要] A case of hereditary nonspherocytic hemolytic disease is reported. The patient presented the clinical picture of hemolytic disease of the newborn infant at birth; however, laboratory studies confirmed the correct diagnosis. Family study revealed the mother to have a similar but milder hemolytic anemia. Splenectomy in the patient at 10 months of age was not beneficial. Differential diagnosis is briefly discussed. The nature of the red cell defect responsible for the condition is unknown. This study points out that hereditary nonspherocytic hemolytic anemia should be considered in patients with the clinical picture of erythroblastosis fetalis who fail to have the expected laboratory findings of that disease.

[学科分类] 儿科学