"AMNIOTIC INFECTION SYNDROME" AND PROPHYLACTIC THERAPY FOR THE NEWBORN INFANT

[摘要] IN 1953 it was proposed that the selection of newborn infants to receive antibacterial therapy should be on the basis of histologic demonstration of placentitis and not on clinical grounds alone. The proposal was based on the finding, already well substantiated by others, of a good correlation between perinatal pneumonia and placentitis. An essential point was that the correlation between clinical suspicion of infection and placental inflammation was good, but not constant. Thus dependence on clinical criteria alone might leave one in the position where a child born after an essentially normal delivery could have been heavily infected and still be denied the benefit of antibiotics.

[学科分类] 儿科学