PERSISTENCE OF IMMUNITY FOLLOWING MONOVALENT AND COMBINED LIVE MEASLES, MUMPS, AND RUBELLA VIRUS VACCINES

[摘要] Neutralizing antibody following Jeryl Lynn mumps virus vaccine persisted for at least six years after vaccination without substantial decline in titer, and protective immunity was solidly retained through the sixth observation year. Hemagglutination-inhibiting antibodies following vaccination with Enders' original Edmonston and more attenuated Moraten and Schwarz lines measles vaccines were retained in comparable level through the fourth year.Antibody following HPV-77 duck rubella vaccine was retained without important decline for at least 3½ years. The pattern for antibody persistence following combined measles-mumps-rubella and mumps-rubella vaccine measured at three years and for measles-rubella vaccine measured at two years was the same as for the monovalent vaccines indicating no alteration in the retention of immunity. None of the children in this study lost his antibody completely. Subclinical reinfection evidenced by antibody increase was commonly seen in vaccinated persons.

[学科分类] 儿科学