RELATION OF OPTIC NEURITIS TO MULTIPLE SCLEROSIS IN CHILDREN

[摘要] Eight children of a previously reported series of 30 with optic neuritis of unknown cause were found to have developed multiple sclerosis in variable periods after the episode of visual failure. The clinical findings are reported here in detail. There were no distinctive characteristics of the ocular findings to indicate those who would eventually show evidence of multiple sclerosis, although simultaneous bilateral involvement and papillitis would appear to be seen more frequently in the children than in the adults who later developed multiple sclerosis. Six of the eight children developed evidence of dissemination within a 2½-year period. In the other two, dissemination did not occur until 12 and 16 years later.

[学科分类] 儿科学