MALIGNANT LYMPHOMA IN CHILDREN

[摘要] On the basis of observations made on 76 children with malignant lymphoma, of whom 28 had Hodgkin's disease (25 with Hodgkin's granuloma and 3 with Hodgkin's sarcoma) and 48 had lymphosarcoma, the following conclusions are drawn: Hodgkin's granuloma has a fairly prolonged course in childhood with a relatively good outlook for 5-year survival, but late recurrences are more common than in the lymphosarcoma group. Lymphosarcoma, excluding giant follicular lymphoma, has a more rapidly malignant course than does Hodgkin's granuloma, but long-term survival does occur in instances of localized disease involving the peripheral nodes on the small intestine. Chemotherapy and radiation therapy provide effective means for controlling Hodgkin's disease and giant follicular lymphoma, even when disease is widespread. Localized disease, when it occurs in malignant lymphoma, requires vigorous radiation treatment. In selected cases, radical surgical removal prior to radiation is indicated. The outlook for these patients is good.

[学科分类] 儿科学