已收录 272983 条政策
 政策提纲
  • 暂无提纲
A Simple and Rapid Spectrophotometric Method for the Determination of Artesunate in Pharmaceuticals
[摘要] Simple and rapid spectrophotometric method for the determination of artesunate is described. The method is based on the reaction of  H2O2, generated by the cleavage of endoperoxide linkage of artesunate and its reaction with potassium iodide to liberate iodine. The liberated iodine bleaches the red colored Safranin O to colorless species and is measured at 521 nm while it oxidizes colorless Variamine blue to violet colored species and is measured at 556 nm. The optimum reaction conditions and other analytical parameters were evaluated. The statistical evaluation of the method is examined by determining intra-day and inter-day precision. The method has been successfully applied to both pure and tablet dosage forms
[发布日期]  [发布机构] 
[效力级别]  [学科分类] 分析化学
[关键词] Spectrophotometry; Artesunate; Falcigo; Safranin O; Variamine blue [时效性] 
   浏览次数:3      统一登录查看全文      激活码登录查看全文