Quantification and Integrity Analysis of DNA in the Stool of Colorectal Cancer Patients May Represent a Complex Alternative to Fecal Occult Blood Testing

[摘要] I read with interest the reports by Klaassen et al. (1) and Boynton et al.(2) published in the July issue of Clinical Chemistry . The first study demonstrated increased amounts of human DNA in the feces of patients with colorectal tumors compared with healthy persons (1), and the second study showed that the majority of DNA isolated from the stools of patients with colorectal tumors was of high molecular weight, in contrast to the fragmented …

[学科分类] 过敏症与临床免疫学