Biological Variation of Procalcitonin in Healthy Individuals

[摘要] Procalcitonin (PCT) is a stable 116-amino acid precursor molecule to the hormone calcitonin. High serum concentrations have been reported in patients with severe systemic bacterial or fungal, but not viral, infections (1).Information on the biological variation of PCT is not available; this is limiting because the clinical utility of laboratory data can be affected by physiologic variation (2). Here we report the results of a study to determine the biological variation of PCT.To investigate the biological variation of this analyte, we followed the same protocol that we used for the study of the biological variation of N-terminal pro-B-type natriuretic peptide (3 …

[学科分类] 过敏症与临床免疫学