The Ultramicro Determination of Salicylates in Biologic Fluids

[摘要] A method for determining salicylates in ultramicro volumes of blood, spinal fluid, and urine has been investigated. This method combines the simplicity of one reagent for color development and deproteinization with a high degree of accuracy and precision. Apparent salicylate values in blood and spinal fluid of normal individuals are of the order of 0.7 mg./100 ml.The application of this method to analysis of capillary samples of blood would be of value in the treatment of salicylate poisoning in children and in the maintenance of therapeutic salicylate levels in pediatric practice.

[学科分类] 过敏症与临床免疫学