Commentary

[摘要] Fulminant hepatic failure is a life-threatening condition with a poor prognosis, and clinical assessment typically focuses on the 3 most common causes: viral hepatitis, alcoholic liver disease, and drug toxicity. Less frequent causes include biliary obstruction and several chemical and biological toxins. Drug-induced liver failure is most often due to acetaminophen (paracetamol) overdose. Measurement of plasma acetaminophen concentrations, in combination with the Rumack–Matthew nomogram, is helpful for predicting the extent of toxic injury to the liver (with ingestion of a single, large …

[学科分类] 过敏症与临床免疫学