Properties of "Usual" and " Atypical" Serum Cholinesterases Using o-Nitrophenyl Butyrate as Substrate

[摘要] The effects of varying concentrations of sodium chloride and formaldehyde on the activity of "usual" and "atypical" serum cholinesterases using o-nitrophenyl butyrate as substrate have been examined. The atypical enzyme has been shown to be more sensitive to either inhibitor than the usual enzyme. These results indicate two new methods for differentiating the two variants using a noncholine ester as substrate. Differential inhibition of the two enzymes by sodium chloride has been shown to be temperature-dependent.

[学科分类] 过敏症与临床免疫学