Brachial artery diameter and velocity of blood flow after hyperemia during the six hours following consumption of cranberry juice

[摘要] The effects of cranberry juice consumption on brachial artery diameter andvelocity of blood flow were investigated. Subjects were aged 40-69 years withdocumented cardiovascular disease. Subjects refrained from alcohol, fruit juices, orcalcium-channel blockers for 24 hours, and supplements 5 days prior to testing. Theyfasted 9 hours prior to the study. Subjects were randomly assigned to an experimentalgroup (n = 6) or a control group (n = 7). Baseline measurements were collected, afterwhich participants drank 3 mUkg of pure cranbeny juice, or 3 mUkg of an isocaloricsugar water mixture (control), and were given half of a plain bagel to eat. Ultrasound andDoppler flow methods were used to measure brachial artery diameter usi~:g a longitudinal(M-mode) and cross-sectional technique at pre-cuff and 2 minutes after cuff removal.Velocity of blood flow was measured at pre-cuff, maximum flow, and 1 and 2 minutesafter cuff removal. Arterial blood pressure was measured with a manualsphygmomanometer. Measurements were repeated at Hours 2,4, and 6. There was asignificant difference (p < 0.05) between the cross-sectional and M-mode method. Therewere no significant differences in diameter values, velocity of blood flow values, meanarterial pressure, and resistance between the control and CBJ groups at any time point. Ingeneral, these measurements significantly decreased (p < 0.05) over time.

[发布机构] University of Wisconsin

[效力级别] Cranberries - Health aspects

[关键词] Blood flow;Cranberries - Health aspects;Cranberries - Physiological effect