How Well Do Laboratories Adhere to Recommended Clinical Guidelines for the Management of Myocardial Infarction? The Italian Experience

[摘要] To the Editor:The Cardiac Marker Guidelines Uptake in Europe (CARMAGUE)1 study (1) pointed out the current use of evidence-based guidelines for the utilization of cardiac biomarkers in Europe (EU) and North America (NA). However, the Southern European countries (Italy, Spain, Portugal, and France) are noticeably underrepresented in the survey. The 2013 Third Italian Survey on the use of cardiac biomarkers (2) by the Working Group on Myocardial Markers (GdS MM) of the Italian Society for Clinical Pathology and Laboratory Medicine (SIPMeL) could usefully integrate the CARMAGUE results for a more comprehensive picture of the worldwide penetration of evidence-based guidelines in this field. The Italian survey, based on a 47-item questionnaire compiled via the Web or during societal educational meetings, produced 126 valid responses from laboratories serving intensive care units (72%) and local laboratories (28%). The composition of responders was sufficiently similar to the CARMAGUE sample (central/teaching hospitals 50%; district/community hospitals 39%) to allow a comparison. It was focused on myocardial markers measured, cardiac troponin (cTn) analytical and preanalytical factors (including internal quality control and external quality assessment, turnaround time, specimen of choice, sampling times, methods, and instruments), cTn decision limits and …

[学科分类] 过敏症与临床免疫学