Commentary

[摘要] This very interesting report communicates a case of acquired HDL-C deficiency that is remarkable for its infectious origin. Very low or undetectable HDL-C more often originates from assay interference from paraproteins and autoantibodies or secondary to the use of drugs, including anabolic steroids and fibrates. Infectious diseases often induce several responses that may hypothetically reduce HDL-C concentrations; impairment of macrophage activity; a humoral immune response that cross-reacts with reagents in enzymatic HDL …

[学科分类] 过敏症与临床免疫学