Solvent Coagulation of Serum Proteins

[摘要] The usefulness of 14 common organic solvents in lowering the temperature necessary for the heat coagulation of serum proteins is evaluated. Six of the compounds, when added to serum in final concentrations varying from 14.3 to 28.6% (v/v), result in the formation of a firm clot at 60°. Ethylene glycol monomethyl ether is effective at 50° at 22.8% (v/v). Lower concentrations are effective at higher temperatures. The boiling points of the six range from 65° (methanol) to 153° (N,N-dimethyl formamide).

[学科分类] 过敏症与临床免疫学