In Reply

[摘要] We thank Dr. Krouwer for his constructive suggestions regarding the total error modeling strategy as recently presented in Van Herpe et al. (1). We agree that, from a mathematical point of view, the probability of glucose meter results falling in the D zone should not be zero for a real meter with a total error below the accuracy threshold. As clearly stated in our work, we formulated this conclusion only in the scope of the executed simulations. Although the number of simulations was high compared to alternative simulation studies in this field, it does not imply a 100% guarantee for future real behavior. Risk analysis techniques (such as failure mode effects analysis) are complementary to …

[学科分类] 过敏症与临床免疫学