Assessment of Vitamin B1 Status

[摘要] The excellent report by Talwar et al. (1) promotes the measurement of thiamin diphosphate (TDP) for the assessment of vitamin B1 status. My experience with >30 000 people supports this, but only for the investigation of untreated patients.The TDP assay is more precise than the transketolase activation (ETK) test, and the method described is an important advance for which I thank the authors. In comparing the two methods, Talwar et al. (1) found TDP slightly advantageous in the identification of B1 deficiency. They and most workers using the ETK test agree that the cutoff point is 25%. I have found it useful to report results in the range 15–25% as borderline. When this is done, there is little … [↵][1]aAuthor for correspondence. [1]: #xref-corresp-1-1

[学科分类] 过敏症与临床免疫学