In Vitro Formation of Ammonia in Blood of Dog and Man

[摘要] A significant (p <0.001) difference was found in the rate of ammonia formation and the amount formed in heparinized dog and human blood at 4°C. The initial ammonia concentration and the increase in ammonia formation with time were correlated for human blood. This in vitro ammonia formation was not prevented by certain enzyme inhibitors, but it continued after cells and plasma were exhaustively dialyzed against water or saline, suggesting that it originates from enzyme action.

[学科分类] 过敏症与临床免疫学