Review of The Metabolic Syndrome. Christopher D. Byrne and Sarah H. Wild, eds. Chichester, West Sussex, England: John Wiley & Sons Ltd., 2005, 432 pp., $110.00, hardcover. ISBN 0-470-02511-5.

[摘要] This book ambitiously reviews a subject that is undergoing shifts in popularity at a rate equaled only by the speed of identification of relevant adipocytokines and inflammatory markers. Nevertheless, the editors tackle the controversial topic with ease and competence. The collection highlights the underpinning elements of the metabolic syndrome—excess visceral adipose tissue fostering poor responses to oxidative stress and inflammation, which worsen and are worsened by insulin resistance and lead to vascular dysfunction. Although the clinician easily recognizes the phenotype of abdominal obesity with its accompanying complications, the details of the pathophysiology are exceedingly complex, and the text serves to clarify underlying themes, if not to render them simple, which they are not. Cardiovascular disease and diabetes are the tip of the iceberg of …

[学科分类] 过敏症与临床免疫学