Prenatal Diagnosis of Genetic Disorders: Trials and Tribulations

[摘要] Prenatal detection of genetic disorders by amniocentesis in the second trimester of pregnancy, followed by studies of amniotic fluid cells, has added a new dimension to genetic counseling. This paper reviews the technique, indications, results, and complications, with emphasis on the problem of interpretation of results, particularly in the detection of fetuses with metabolic diseases.

[学科分类] 过敏症与临床免疫学