The Interference of Chlorpromazine Metabolites in the Analysis of Urinary Methoxy-Catecholamines

[摘要] The analysis of urinary methoxy-catecholamines by the method of Pisano (1) could not be applied to the urine of patients who were receiving chlorpromazine. Chlor-promazine and the chlorpromazine metabolites, 7-hydroxychlorpromazine and chlor-promazine sulfoxide, were shown to interfere with the column chromatographic separation and spectrophotometric analysis of the methoxy-catecholamines.

[学科分类] 过敏症与临床免疫学