Quantitative Analysis of Urinary 17-Oxogenic Steroids Using Sodium Metaperiodate Oxidation

[摘要] At 550° the oxidation of pregnane-17, 20-diols (17- oxogenic steroids) to 17-oxosteroids with sodium metaperiodate is complete within 10 mm. The yield of 17-oxosteroids is not affected by light or pH's between 4.6 and 7.0. The 17-oxgenic steroids may be oxidized in the presence of glucose provided that additional sodium metaperiodate, equivalent in amount to or in excess of the glucose, is used for oxidation.

[学科分类] 过敏症与临床免疫学