The Third Universal Definition of Myocardial Infarction—Moving Forward

[摘要] The third iteration of the Universal Definition of Acute Myocardial Infarction (AMI) was recently published (1). The guidelines expand on previous information. Salient features include: 1. Cardiac troponin remains the biomarker of choice for the diagnosis of each type of AMI.2. Criteria for AMI include a rising and/or falling pattern of troponin values with at least 1 >99th percentile value.3. Assays should ideally have a 10% CV at the 99th percentile to best maximize the ability to define significant changes; however, assays with CVs up to 20% do not cause false-positive values and are clinically usable.4. Because troponin criteria for a rising and/or falling pattern are assay dependent, generalized concentration or percentage changes could not be specified.5. With high-sensitivity assays, sex-specific 99th …

[学科分类] 过敏症与临床免疫学