The Silent Cry of the Kidneys

[摘要] > When blood flow through the renal artery slows down,> > Due to lack of oxygen renal tubular cells start to frown:> > Their mighty mitochondria within are unable to generate> > The energy rich molecules of ATP at the optimal rate.> In the cytosolic fraction calcium ions start to accumulate;> > The calcium-dependent phospholipases they begin to activate.> > Membrane phospholipids disintegrate, structural integrity is lost,> > Cellular polarity reversed, brush border enzymes are cast.> Desquamation of epithelial cells leaves the basement layer exposed;> > The dead …

[学科分类] 过敏症与临床免疫学