Commentary

[摘要] Prolonged paralysis due to low butyrylcholinesterase (BChE) activity after suxamethonium administration arises from either an inherited or an acquired deficiency, but the risk of prolonged paralysis is dependent on both enzyme activity and genotype. BCHE is a highly polymorphic gene, and the prevalences of the different mutations show large geographic and ethnic variation. The terminology can be challenging (1). Biochemical phenotypes are defined by the pattern of values obtained after differential enzyme inhibition to determine “inhibitor numbers,” …

[学科分类] 过敏症与临床免疫学