Commentary

[摘要] This case highlights the significance of altered bone metabolism on bone mass and quality. In this patient, the increased CK-BB fraction strongly suggests osteopetrosis. Clinically, her presentation is most consistent with the intermediate disease form whereby affected persons have short stature, increased risk for cranial nerve deficits due to passage through narrowed skull foramina, increased risk for low-trauma fractures owing to poor bone quality, dental/tooth abnormalities, and anemia from crowding of the bone marrow …

[学科分类] 过敏症与临床免疫学