'n Ondersoek na die antibakteriese eienskappe van Carpobrotus edulis L.

[摘要] English: In the folk medicine of South Africa, many traditional medicinal plants areused by both the rural and a small percentage of the city population. One ofthese plants is Carpobrotus edulis L. An investigation of the chemicalcomposition as well as the anti-microbial properties of this plant was themain objective of this study.Overviews on traditional medicine in South Africa and the familyMesembryanthemaceae are given. According to the available literature littleis known about the chemical composition, active substances in as well aspharmacological properties of C. edulis, but most of the publishedinformation deals with the ecological importance of the plant. In this studythe anti-bacterial properties of the plant were confirmed and three semipurifiedfractions were initially isolated by applying differentchromatography techniques.During purification of active substances, with prior removal of tannins, sixanti-bacterial compounds were isolated of which five were identified namelyrutin, neohesperidin, hyperoside, cactecin, ferulic acid while one flavonoidremained unidentified.The conclusion from this study is that the anti-bacterial properties of theplant are related to the presence of the tlavonoids rutin, neohesperidin,hyperoside, cactecin and femlic acid as well as one unknown flavonoid.The most prormsmg observation during this study was the selectiveinhibition of gram negative bacteria, known to be more resistant than grampositive bacteria to antibioticums.

[发布机构] University of the Free State