Functional properties of soybean nodulin 26 from a comparative three‐dimensional model
[摘要] A model of the nodulin 26 channel protein has been constructed based on comparative modeling and molecular dynamics simulations. Structural features of the protein indicate a selectivity filter that differs from those of the known structures of Escherichia coli glycerol facilitator and mammalian aquaporin 1. The model structure also reveals important roles of Ser207 and Phe96 in ligand binding and transport.
[发布日期] [发布机构]
[效力级别] [学科分类] 生物化学/生物物理
[关键词] Nodulin-like intrinsic protein;Comparative model;Transmembrane helix;Selectivity filter;Formamide;AQP;aquaporin;GlpF;glycerol facilitator;SM;symbiosome membrane;NIP;nodulin-like intrinsic protein;TIP;tonoplast intrinsic protein;SIP;small basic intrinsic protein;POPE;palmitoyloleyl phosphatidyl-ethanolamine;–NPA–;–Asn–Pro–Ala– [时效性]
