The 65‐kDa protein from pig heart A new substrate for Clostridium botulinum ADP‐ribosyltransferase (exoenzyme C3)

[摘要]

In the pig heart sarcolemma, a 65 kDa protein is found to be ADP-ribosylated by Clostridium botulinum ADP-ribosyltransferase (exoenzyme C₃). ADP-ribosylation of this protein is regulated by guanyl nucleotides and cytosol factor in a fashion similar to that for other C₃ substrates. The new exoenzyme C₃ substrate was partially purified. This protein is supposed to be a GTP-binding one.

[学科分类] 生物化学/生物物理

[关键词] ADP-ribosyltransferase;GTP-binding protein;Pig heart sarcolemma;Clostridium botulinum