Knowledge, attitudes and practices related to isoniazid preventive therapy of adults living with HIV and AIDS in Berea district, Lesotho

[摘要] Isoniazid preventive therapy is an effective strategy for prevention of tuberculosis among people living with HIV/AIDS. However, its uptake amongst this people is very low. KAP related to isoniazid preventive therapy may play a role in this poor uptake. Thus, the aim of this study was to assess and describe knowledge, attitude and practices related to isoniazid preventive therapy of adults living with HIV in Berea district, Lesotho. A quantitative, descriptive design was used and participants (n=350) were conveniently selected. Structured questionnaire was administered. Descriptive statistics for continuous and categorical data were calculated.This study was guided by theory of planned behaviour (TPB) therefore, knowledge was reflected by behavioural, normative, control beliefs, subjective norms and perceived behavioural control related to isoniazid uptake. Attitude section mirrored participants' attitude towards isoniazid uptake, whereas practice was presented as participants' intention, actual behavioural control and behaviour towards isoniazid uptake.Results were presented as percentage positive scores leading to enhanced isoniazid uptake. Knowledge predicting isoniazid uptake was determined as behavioural beliefs (88.9%), normative beliefs (82.9%), control beliefs (0.3%) and subjective norms (69.0%). Knowledge component favoured isoniazid uptake. Attitudes (78.6%) enhanced isoniazid uptake. Practice was reflected as intention (99.4%), actual behavioural control (98.0%) and behaviour (82.9%). Practice component indicated a strong intention to use isoniazid preventative therapy.Behavioural and normative beliefs, attitude, intention, actual behavioural control and behaviour were high, subjective norms were average, and control beliefs and perceived behavioural control were low.Recommendations were aligned to the TPB and include health promotion, trainings, and community involvement.

[发布机构] University of the Free State