Primary structure of bovine cerebellum GTP‐binding protein G39 and its effect on the adenylate cyclase system

[摘要]

The primary structure of bovine cerebellum GTP-binding protein α-subunit, protein G₃₉ was determined by parallel analysis of the protein amino acid sequence and the corresponding cDNA nucleotide sequence. The protein consists of 354 amino acid residues and has a molecular mass of 40064 Da. High homology between G₃₉ and other G-proteins, especially rat brain G_o was shown. An assumption is made that certain brain adenylate cyclase system properties are determined by the presence of G₃₉.

[学科分类] 生物化学/生物物理

[关键词] GTP-binding protein;Adenylate cyclase;Amino acid sequence;cDNA cloning;Nucleotide sequence;(Bovine cerebellum)